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Early unexplained signs of tachycardia, tachypnea, labile blood pressure and metabolic acidosis may precede temperature elevation. Type your product review in the space provided. In general, the rate of absorption of local anesthetic agents following topical application occurs most rapidly after intratracheal administration. These changes may be attributable to a direct depressant effect of the local anesthetic agent on various components of the cardiovascular system. Marketing Information LIDOCAINE HYDROCHLORIDE. Cheeks Cosmetic Accessories Eyes Face Lips Nails Fragrances.